HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: AP2M1 (P84092)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	32357304
Identification Methods	cross-linking study, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 752 Rn			1 435
+	Rn
		98739 F1LST4_RAT (1-751): 7.66e-96: 316: 99.87		AP2M1_RAT (1-435): 3.72e-180: 511: 100.00
+	Mm
		530788 TAU_MOUSE (1-752): 8.48e-83: 280: 89.26		AP2M1_MOUSE (1-435): 3.72e-180: 511: 100.00
+	Hs
		530201 TAU_HUMAN (1-752): 1.05e-71: 251: 71.98		AP2M1_HUMAN (1-435): 3.72e-180: 511: 100.00
+	Hs
		530328 TAU_HUMAN (1-752): 1.05e-71: 251: 71.98		AP1M1_HUMAN (2-434): 4.83e-171: 487: 38.85
+	Hs
		698340 MAP4_HUMAN (4-752): 1.25e-32: 138: 18.03		AP2M1_HUMAN (1-435): 3.72e-180: 511: 100.00
+	Hs
		530624 TAU_HUMAN (1-752): 1.05e-71: 251: 71.98		AP3M1_HUMAN (1-434): 1.85e-124: 368: 24.66
+	Hs
		529404 TAU_HUMAN (1-752): 1.05e-71: 251: 71.98		AP3M2_HUMAN (1-434): 3.3e-120: 358: 24.89
+	Hs
		215941 SYNJ1_HUMAN (369-746): 5.36e-09: 61.9: 10.57		AP2M1_HUMAN (1-435): 3.72e-180: 511: 100.00
+	Dm
		264443 Q9VLS7_DROME (16-561): 6.95e-11: 68.2: 10.11		O62530_DROME (1-435): 6.83e-172: 490: 86.56