HitPredict

Interactor 1: FSHR (P23945)
Follicle-stimulating hormone receptor (FSH-R) (Follitropin receptor)
Gene: FSHR

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	15196694, 20600589
Identification Methods	two hybrid, affinity chromatography technology, lex-a dimerization assay, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 695 Hs			1 245
+	Hs
		646721 MTR1B_HUMAN (347-665): 3.6e-68: 229: 19.88		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		815858 MTR1A_HUMAN (363-662): 1.34e-67: 227: 19.05		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683200 MTR1B_HUMAN (347-665): 3.6e-68: 229: 19.88		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		683198 MTR1A_HUMAN (363-662): 1.34e-67: 227: 19.05		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		680103 SSR4_HUMAN (366-646): 8.17e-59: 205: 18.21		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		428927 ADRB2_HUMAN (347-668): 1.25e-59: 208: 15.60		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		680100 SSR4_HUMAN (366-646): 8.17e-59: 205: 18.21		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	At
		965375 BRL2_ARATH (1-210): 6.82e-26: 116: 13.56		14332_ARATH (3-243): 8.65e-144: 404: 61.22
+	At
		788683 BRL2_ARATH (1-210): 6.82e-26: 116: 13.56		14333_ARATH (3-243): 8e-143: 401: 61.63
+	Hs
		600725 DRD1_HUMAN (367-688): 6.16e-60: 209: 14.44		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		680104 SSR4_HUMAN (366-646): 8.17e-59: 205: 18.21		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		927479 LGR4_HUMAN (173-412): 4.84e-21: 100: 14.34		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		905066 LGR4_HUMAN (173-412): 4.84e-21: 100: 14.34		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33