Interactor 1: IL4RA (P24394)
Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124) [Cleaved into: Soluble interleukin-4 receptor subunit alpha (Soluble IL-4 receptor subunit alpha) (Soluble IL-4R-alpha) (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)]
Gene: IL4R

Interactor 2: TYK2 (P29597)
Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)
Gene: TYK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.628

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0019221 - cytokine-mediated signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 825
Hs

1 1187
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024