Protein: OPTN
Optineurin

Gene: OPTN
Organism: Mus musculus
Interactions: 13
UniProt ID: Q8K3K8

Gene Ontology (top 5):
GO:0001920 - negative regulation of receptor recycling
GO:0005776 - autophagosome
GO:0005794 - Golgi apparatus
GO:0005802 - trans-Golgi network
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1317374

TBK1
Serine/threonine-protein kinase TBK1

4

20

Small-scale

0.692

High

1189685

HACE1
E3 ubiquitin-protein ligase HACE1

1

9

Small-scale

0.635

High

1317372

OPTN
Optineurin

1

19

Small-scale

0.618

High

312161

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

20

Small-scale

0.579

High

1225662

SQSTM
Sequestosome-1

1

9

Small-scale

0.550

High

370858

FOS
Protein c-Fos

1

6

Small-scale

0.501

High

108777

G3X9H5
Huntingtin

1

7

Small-scale

0.479

High

976721

RB11A
Ras-related protein Rab-11A

1

10

Small-scale

0.479

High

1221639

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

20

Small-scale

0.479

High

1317373

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

11

Small-scale

0.479

High

669427

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

12

Small-scale

0.437

High

1223858

SEM4A
Semaphorin-4A

1

1

Small-scale

0.437

High


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Last updated: 11Aug2025