HitPredict

Interactor 1: GRIA2 (P19491)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: GRIA3 (P19492)
Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3)
Gene: GRIA3

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.906

The method score is based on:

Property Details
Experiments 1309749, 26966189, 30975770, 21317873
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, x-ray crystallography, transmission electron microscopy, 3D electron microscopy, electron microscopy 3D single particle reconstruction, anti bait coimmunoprecipitation, cosedimentation in solution
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001919 - regulation of receptor recycling
GO:0004970 - glutamate-gated receptor activity
GO:0004971 - AMPA glutamate receptor activity
GO:0005886 - plasma membrane
and 24 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 883
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1 888
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Last updated: 11Aug2025