HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 375
+	Hs
		625278 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		625343 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		ACTS_HUMAN (2-375): 0: 594: 93.85
+	Hs
		841152 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		841154 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		841156 CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00		ACTS_HUMAN (2-375): 0: 594: 93.85