HitPredict

Interactor 1: CXCR2 (P25025)
C-X-C chemokine receptor type 2 (CXC-R2) (CXCR-2) (CDw128b) (GRO/MGSA receptor) (High affinity interleukin-8 receptor B) (IL-8R B) (IL-8 receptor type 2) (CD antigen CD182)
Gene: CXCR2

Interactor 2: LASP1 (Q14847)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.50	0.567

Property	Details
Experiments	20419088, 21876773
Identification Methods	anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 360 Hs			1 261
+	Hs
		830625 CXCR3_HUMAN (21-357): 3.8e-79: 248: 40.71		LASP1_HUMAN (1-261): 1.82e-58: 188: 100.00
+	Hs
		625738 CXCR1_HUMAN (18-349): 2.54e-69: 222: 78.92		LASP1_HUMAN (1-261): 1.82e-58: 188: 100.00
+	Hs
		895623 CXCR4_HUMAN (15-329): 1.86e-67: 217: 33.54		LASP1_HUMAN (1-261): 1.82e-58: 188: 100.00
+	Hs
		686771 CCR1_HUMAN (31-359): 4.61e-70: 224: 30.51		DBNL_HUMAN (59-261): 2.02e-25: 105: 23.65
+	Hs
		686731 CCR1_HUMAN (31-359): 4.61e-70: 224: 30.51		SH3G1_HUMAN (48-261): 6.99e-24: 100: 18.81