HitPredict

Interactor 1: IF2B (P20042)
Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF2-beta)
Gene: EIF2S2

Interactor 2: LTK (P29376)
Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)
Gene: LTK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 333 Hs			1 864
+	Hs
		541330 IF2B_HUMAN (1-333): 4.05e-148: 422: 100.00		FGFR1_HUMAN (221-839): 2.46e-139: 435: 20.32
+	Hs
		627593 IF2B_HUMAN (1-333): 4.05e-148: 422: 100.00		FGFR3_HUMAN (100-834): 2.09e-138: 432: 20.89
+	Hs
		465402 IF2B_HUMAN (1-333): 4.05e-148: 422: 100.00		IGF1R_HUMAN (298-854): 3.96e-128: 419: 27.39
+	Hs
		477206 IF2B_HUMAN (1-333): 4.05e-148: 422: 100.00		ROS1_HUMAN (510-813): 5.37e-80: 285: 45.93
+	Hs
		411336 IF2B_HUMAN (1-333): 4.05e-148: 422: 100.00		NTRK1_HUMAN (502-786): 7.78e-60: 220: 41.64
+	Hs
		627637 IF2B_HUMAN (1-333): 4.05e-148: 422: 100.00		ROR1_HUMAN (504-778): 1.87e-53: 202: 40.00
+	Hs
		411651 IF5_HUMAN (191-308): 2.29e-41: 151: 24.00		NTRK1_HUMAN (502-786): 7.78e-60: 220: 41.64