HitPredict

Interactor 1: RAB3B (P20337)
Ras-related protein Rab-3B (EC 3.6.5.2)
Gene: RAB3B

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF_assoc_1~Ras, Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 219 Hs			1 618
+	Hs
		955960 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		MIRO2_HUMAN (1-618): 0: 795: 100.00
+	Mm
		937161 RAB8A_MOUSE (15-219): 4.29e-101: 293: 47.32		RAB35_MOUSE (5-168): 3.57e-76: 242: 24.70
+	Mm
		937157 RAB8A_MOUSE (15-219): 4.29e-101: 293: 47.32		RAB8B_MOUSE (5-180): 2.03e-71: 230: 18.54
+	Hs
		580963 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		953372 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		955005 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Mm
		956834 RAB8B_MOUSE (15-219): 6.75e-92: 269: 44.39		RAB35_MOUSE (5-168): 3.57e-76: 242: 24.70
+	Hs
		955915 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RHOG_HUMAN (3-170): 1.69e-74: 238: 27.47
+	Hs
		955911 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RAC1_HUMAN (3-181): 3.96e-74: 237: 26.43
+	Dm
		670096 RAB3_DROME (1-219): 2.68e-93: 273: 76.02		Q9W5X0_DROME (5-180): 2.22e-72: 232: 20.79
+	Hs
		902181 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RAB13_HUMAN (5-180): 7.62e-73: 234: 20.23
+	Hs
		955910 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RAB1A_HUMAN (5-172): 9.26e-73: 234: 20.59
+	Hs
		955907 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RB11A_HUMAN (5-202): 4.27e-72: 232: 19.00
+	Hs
		955902 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RAB8A_HUMAN (5-187): 4.8e-71: 229: 17.30
+	Hs
		955909 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RHOB_HUMAN (6-168): 4.59e-13: 70.1: 29.38
+	Hs
		955905 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RHOA_HUMAN (6-168): 1.75e-11: 65.5: 28.25
+	Hs
		956011 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RHOF_HUMAN (2-167): 3.39e-11: 65.1: 26.67
+	Hs
		466179 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		126530 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		601226 RAB8A_HUMAN (15-219): 7.2e-92: 269: 46.83		RHOQ_HUMAN (5-169): 2.03e-10: 62.8: 26.26