HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: OSBL9 (Q96SU4)
Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9)
Gene: OSBPL9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 736
+	Hs
		901000 RAB5C_HUMAN (1-215): 3.9e-85: 252: 86.57		OSBL9_HUMAN (1-736): 0: 730: 100.00
+	Hs
		976503 RB11A_HUMAN (11-215): 2.1e-82: 245: 38.32		OSBL9_HUMAN (1-736): 0: 730: 100.00
+	Hs
		631449 RAB5A_HUMAN (1-215): 2.08e-88: 260: 100.00		OSB10_HUMAN (3-730): 0: 540: 36.02
+	Hs
		631448 RAB5A_HUMAN (1-215): 2.08e-88: 260: 100.00		OSB11_HUMAN (7-729): 3.9e-180: 534: 37.08
+	Hs
		901016 RAB5C_HUMAN (1-215): 3.9e-85: 252: 86.57		OSB11_HUMAN (7-729): 3.9e-180: 534: 37.08
+	Hs
		976529 RB11A_HUMAN (11-215): 2.1e-82: 245: 38.32		OSB10_HUMAN (3-730): 0: 540: 36.02
+	Hs
		976528 RB11A_HUMAN (11-215): 2.1e-82: 245: 38.32		OSB11_HUMAN (7-729): 3.9e-180: 534: 37.08
+	Dm
		95046 RAB5_DROME (6-213): 8.2e-98: 285: 75.00		E1JH23_DROME (302-677): 1.78e-133: 402: 55.27
+	Hs
		631454 RAB5A_HUMAN (1-215): 2.08e-88: 260: 100.00		OSBL8_HUMAN (156-724): 6.09e-134: 419: 28.43
+	Hs
		901020 RAB5C_HUMAN (1-215): 3.9e-85: 252: 86.57		OSBL8_HUMAN (156-724): 6.09e-134: 419: 28.43
+	Hs
		976537 RB11A_HUMAN (11-215): 2.1e-82: 245: 38.32		OSBL8_HUMAN (156-724): 6.09e-134: 419: 28.43
+	Dm
		1463797 RAB5_DROME (6-213): 8.2e-98: 285: 75.00		Q9W0K9_DROME (7-114): 4.9e-16: 79.7: 37.50