HitPredict

Interactor 1: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Interactor 2: ERC6L (Q2NKX8)
DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like) (PLK1-interacting checkpoint helicase) (Tumor antigen BJ-HCC-15)
Gene: ERCC6L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 801 Hs			1 1250
+	Hs
		229311 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		SMCA5_HUMAN (16-1037): 0: 635: 21.42
+	Hs
		631352 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		SMCA1_HUMAN (16-1020): 0: 627: 21.58
+	Hs
		631414 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		CHD3_HUMAN (21-1080): 0: 610: 18.53
+	Hs
		631380 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		SMCA4_HUMAN (14-896): 0: 605: 21.05
+	Hs
		631426 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		CHD4_HUMAN (24-992): 0: 588: 18.51
+	Hs
		631379 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		SMCA2_HUMAN (38-982): 0: 586: 19.12
+	Hs
		229407 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		SMCA5_HUMAN (16-1037): 0: 635: 21.42
+	Hs
		658677 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		SMCA1_HUMAN (16-1020): 0: 627: 21.58
+	Hs
		151415 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		CHD1_HUMAN (30-1070): 0: 608: 19.62
+	Hs
		846977 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		SMCA4_HUMAN (14-896): 0: 605: 21.05
+	Hs
		1059625 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		CHD4_HUMAN (24-992): 0: 588: 18.51
+	Hs
		846778 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		SMCA2_HUMAN (38-982): 0: 586: 19.12
+	Hs
		229252 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		SMCA5_HUMAN (16-1037): 0: 635: 21.42
+	Hs
		243979 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		SMCA1_HUMAN (16-1020): 0: 627: 21.58
+	Hs
		1067158 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		HELLS_HUMAN (94-682): 0: 570: 26.85
+	Hs
		846993 BRDT_HUMAN (48-763): 4.45e-106: 349: 45.39		SMCA4_HUMAN (14-896): 0: 605: 21.05
+	Hs
		244356 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		CHD3_HUMAN (21-1080): 0: 610: 18.53
+	Hs
		151361 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		CHD1_HUMAN (30-1070): 0: 608: 19.62
+	Hs
		244139 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		SMCA4_HUMAN (14-896): 0: 605: 21.05
+	Hs
		244138 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		SMCA2_HUMAN (38-982): 0: 586: 19.12