HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: RHG23 (Q9P227)
Rho GTPase-activating protein 23 (Rho-type GTPase-activating protein 23)
Gene: ARHGAP23

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	32203420
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1491
+	Hs
		70663 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MYO9A_HUMAN (134-1403): 5.16e-136: 468: 12.33
+	Hs
		900443 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MYO9B_HUMAN (218-1352): 1.22e-114: 403: 14.24
+	Mm
		1265268 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		SRGP1_MOUSE (608-1480): 2.51e-96: 337: 14.75
+	Hs
		900637 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SRGP1_HUMAN (609-1480): 5.04e-92: 325: 15.15
+	Hs
		900429 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG05_HUMAN (521-1120): 1.71e-80: 295: 15.64
+	Hs
		900540 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG29_HUMAN (479-1489): 2.32e-80: 292: 13.75
+	Hs
		900954 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG35_HUMAN (521-1127): 2.77e-76: 281: 15.76
+	Hs
		900871 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG39_HUMAN (181-1099): 4.8e-76: 277: 15.56
+	Hs
		245183 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		OPHN1_HUMAN (696-1313): 2.38e-77: 276: 14.98
+	Hs
		49631 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG10_HUMAN (922-1245): 5.86e-68: 248: 26.63
+	Hs
		900997 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		GMIP_HUMAN (894-1261): 4.35e-67: 248: 23.17
+	Hs
		900634 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG22_HUMAN (837-1146): 3.61e-67: 243: 23.12
+	Hs
		64681 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG32_HUMAN (879-1226): 1.46e-62: 238: 21.16
+	Hs
		900426 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ABR_HUMAN (882-1099): 9.08e-63: 233: 32.74
+	Mm
		925793 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		ABR_MOUSE (819-1099): 7.7e-63: 233: 27.93
+	Hs
		900564 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG21_HUMAN (31-784): 3.88e-49: 195: 23.81
+	Hs
		506561 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		BCR_HUMAN (915-1069): 2.76e-21: 103: 40.00
+	Mm
		1125742 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		RHG01_MOUSE (901-1073): 2.2e-20: 97.8: 32.00
+	Hs
		900412 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG01_HUMAN (901-1073): 1.34e-20: 98.6: 33.14
+	Mm
		925791 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		RHG01_MOUSE (901-1073): 2.2e-20: 97.8: 32.00