HitPredict

Interactor 1: DCC1 (P25559)
Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1)
Gene: DCC1

Interactor 2: CTF18 (P49956)
Chromosome transmission fidelity protein 18
Gene: CTF18

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.739

Property	Details
Experiments	15964801, 26987677, 26250113, 32585006, 16554755, 37968396, 21179020
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007064 - mitotic sister chromatid cohesion GO:0031390 - Ctf18 RFC-like complex GO:0035753 - maintenance of DNA trinucleotide repeats
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 380 Sc			1 741
+	Sc
		634049 DCC1_YEAST (1-380): 0: 514: 100.00		RFC1_YEAST (12-701): 4.3e-82: 281: 15.11
+	Sc
		634057 DCC1_YEAST (1-380): 0: 514: 100.00		RFC2_YEAST (103-466): 8.14e-79: 258: 16.49
+	Sc
		634056 DCC1_YEAST (1-380): 0: 514: 100.00		RFC4_YEAST (113-422): 5.98e-70: 233: 19.37
+	Sc
		634048 DCC1_YEAST (1-380): 0: 514: 100.00		RFC3_YEAST (103-433): 3.34e-65: 221: 16.33
+	Hs
		1261217 DCC1_HUMAN (17-380): 3.81e-127: 373: 23.00		CTF18_HUMAN (74-739): 7.4e-100: 331: 20.75
+	Hs
		722030 DCC1_HUMAN (17-380): 3.81e-127: 373: 23.00		RFC4_HUMAN (90-466): 1.13e-84: 274: 19.38
+	Hs
		722148 DCC1_HUMAN (17-380): 3.81e-127: 373: 23.00		RFC2_HUMAN (94-440): 5.68e-74: 245: 19.78
+	Hs
		777916 DCC1_HUMAN (17-380): 3.81e-127: 373: 23.00		RFC5_HUMAN (95-427): 9.88e-71: 236: 17.00