Interactor 1: SPB1 (P25582)
27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase (EC 2.1.1.167) (2'-O-ribose RNA methyltransferase SPB1) (AdoMet-dependent rRNA methyltransferase SPB1) (S-adenosyl-L-methionine-dependent methyltransferase) (Suppressor of PAB1 protein 1)
Gene: SPB1

Interactor 2: NOP53 (Q12080)
Ribosome biogenesis protein NOP53 (Nucleolar protein 53)
Gene: NOP53

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.730

The method score is based on:

Property Details
Experiments 25877921, 26317469, 29176610, 37968396, 37811893, unassigned1262
Identification Methods affinity chromatography technology, two hybrid, biochemical, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005730 - nucleolus
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 841
Sc

1 455
+ Hs
+ Dm
+ Sc

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Last updated: 15 Jul 2024