HitPredict

Interactor 1: PWP2 (P25635)
Periodic tryptophan protein 2 (U three protein 1) (U3 small nucleolar RNA-associated protein 1) (U3 snoRNA-associated protein 1)
Gene: PWP2

Interactor 2: GBLP (P38011)
Small ribosomal subunit protein RACK1 (Guanine nucleotide-binding protein subunit beta-like protein) (Receptor for activated C kinase) (Receptor of activated protein kinase C 1) (RACK1)
Gene: ASC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 923 Sc			1 319
+	Hs
		903174 TBL3_HUMAN (79-849): 6.24e-108: 354: 13.69		WDR5_HUMAN (185-318): 4.59e-34: 128: 18.38
+	Hs
		1016312 TBL3_HUMAN (79-849): 6.24e-108: 354: 13.69		SNR40_HUMAN (230-318): 6.37e-13: 70.4: 21.98
+	Hs
		903349 WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95		WDR5B_HUMAN (99-318): 6.63e-59: 193: 21.97
+	Hs
		903551 WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95		NLE1_HUMAN (1-223): 1.25e-56: 192: 25.09
+	Sc
		742918 COPA_YEAST (1-447): 1.7e-49: 192: 12.05		GBLP_YEAST (1-223): 1.48e-40: 145: 18.91
+	Hs
		903418 WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95		FBXW7_HUMAN (92-319): 1.41e-53: 187: 23.38
+	Hs
		863508 COPA_HUMAN (2-394): 3.56e-29: 128: 9.05		FBXW7_HUMAN (92-319): 1.41e-53: 187: 23.38
+	Hs
		792949 WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95		LIS1_HUMAN (134-313): 2.16e-43: 155: 22.53
+	Hs
		903109 WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95		RACK1_HUMAN (1-223): 5.44e-44: 154: 20.09
+	Hs
		903077 WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95		WDR5_HUMAN (185-318): 4.59e-34: 128: 18.38
+	Hs
		863397 COPA_HUMAN (2-394): 3.56e-29: 128: 9.05		WDR5_HUMAN (185-318): 4.59e-34: 128: 18.38
+	Hs
		793026 LIS1_HUMAN (564-720): 5.47e-17: 86.5: 10.06		KTNB1_HUMAN (140-318): 8.17e-44: 160: 20.99
+	Hs
		792935 LIS1_HUMAN (564-720): 5.47e-17: 86.5: 10.06		LIS1_HUMAN (134-313): 2.16e-43: 155: 22.53
+	Mm
		925836 LIS1_MOUSE (564-720): 4.61e-17: 86.5: 10.06		LIS1_MOUSE (134-313): 1.73e-43: 155: 22.53
+	Hs
		792967 LIS1_HUMAN (564-720): 5.47e-17: 86.5: 10.06		RACK1_HUMAN (1-223): 5.44e-44: 154: 20.09
+	Hs
		1288390 WDR3_HUMAN (1-255): 3.01e-41: 165: 15.93		SNR40_HUMAN (230-318): 6.37e-13: 70.4: 21.98
+	Hs
		903428 WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95		SNR40_HUMAN (230-318): 6.37e-13: 70.4: 21.98