Interactor 1: NOT1 (P25655)
General negative regulator of transcription subunit 1 (Cell division cycle protein 39)
Gene: CDC39
Interactor 2: NOT4 (P34909)
General negative regulator of transcription subunit 4 (EC 2.3.2.27) (Modulator of transcription 2)
Gene: MOT2
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.764 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9463387, 12215531, 7926748, 11805826, 25914052, 16263706, 30948432, 18467557, 35357307, 37968396, 20386698, 11823428, 21669201, 28180299, 32299921, 19707589, 21406554, 16429126 |
| Identification Methods | coimmunoprecipitation, two hybrid, tandem affinity purification, affinity chromatography technology, pull down, biochemical, protein complementation assay, x-ray crystallography, molecular sieving, dihydrofolate reductase reconstruction |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0030015 - CCR4-NOT core complex GO:0032968 - positive regulation of transcription elongation by RNA polymerase II |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
