HitPredict

Interactor 1: CSRP1 (P21291)
Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP) (CRP1) (Epididymis luminal protein 141) (HEL-141)
Gene: CSRP1

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21706016
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 217
+	Hs
		987967 PDLI7_HUMAN (68-190): 2.73e-25: 103: 16.54		GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00
+	Hs
		878427 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00
+	Hs
		439995 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		LCK_HUMAN (3-202): 7.98e-34: 128: 28.44
+	Hs
		834155 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		CSK_HUMAN (2-139): 3.94e-24: 100: 36.24
+	Mm
		362452 PAXI_MOUSE (3-123): 6.85e-23: 97.1: 14.05		ABL1_MOUSE (4-139): 4.08e-22: 95.9: 35.46
+	Hs
		593944 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14
+	Hs
		362210 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46
+	Hs
		840935 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		ABL2_HUMAN (4-139): 9.65e-22: 94.7: 34.04
+	Hs
		117131 PDLI7_HUMAN (68-190): 2.73e-25: 103: 16.54		J3QRU1_HUMAN (71-215): 6.6e-12: 65.8: 16.33
+	Hs
		463235 PDLI7_HUMAN (68-190): 2.73e-25: 103: 16.54		YES_HUMAN (71-215): 7.5e-12: 65.8: 16.33
+	Hs
		440442 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58
+	Hs
		463023 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		YES_HUMAN (71-215): 7.5e-12: 65.8: 16.33
+	Ce
		113230 G5EFG1_CAEEL (67-193): 1.58e-21: 93.2: 15.00		SRC2_CAEEL (118-215): 6.76e-13: 68.9: 22.00
+	Hs
		270702 LDB3_HUMAN (7-126): 1.5e-24: 101: 13.93		SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58
+	Hs
		473382 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		HCK_HUMAN (92-215): 4.76e-11: 63.5: 18.90
+	Mm
		431364 PAXI_MOUSE (3-123): 6.85e-23: 97.1: 14.05		SRC_MOUSE (161-215): 3.32e-10: 60.8: 31.58
+	Hs
		557175 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58
+	Hs
		463255 LIMA1_HUMAN (3-117): 9.1e-21: 91: 27.83		YES_HUMAN (71-215): 7.5e-12: 65.8: 16.33
+	Hs
		463403 PAXI_HUMAN (3-123): 9.42e-23: 96.7: 14.05		LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47
+	Hs
		463821 LIMA1_HUMAN (3-117): 9.1e-21: 91: 27.83		LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47