HitPredict

Interactor 1: S1PR1 (P21453)
Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)
Gene: S1PR1

Interactor 2: CELR2 (Q9HCU4)
Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3)
Gene: CELSR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004930 - G protein-coupled receptor activity GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 2923
+	Hs
		351968 S1PR4_HUMAN (1-329): 2.25e-81: 255: 39.76		CELR2_HUMAN (31-2923): 0: 2336: 100.00
+	Hs
		722886 SSR2_HUMAN (8-359): 8.74e-71: 227: 17.96		CELR2_HUMAN (31-2923): 0: 2336: 100.00
+	Hs
		1404956 S1PR3_HUMAN (21-382): 5.87e-64: 210: 51.79		CELR2_HUMAN (31-2923): 0: 2336: 100.00
+	Hs
		638265 S1PR1_HUMAN (1-382): 1.52e-79: 250: 100.00		PCDGD_HUMAN (2-165): 1.23e-16: 89.2: 11.71