HitPredict

Interactor 1: S100P (P25815)
Protein S100-P (Migration-inducing gene 9 protein) (MIG9) (Protein S100-E) (S100 calcium-binding protein P)
Gene: S100P

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 522
+	Hs
		685191 S10AB_HUMAN (2-92): 1.47e-35: 118: 40.66		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		380888 S100B_HUMAN (1-92): 1.7e-31: 107: 50.00		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		301913 HORN_HUMAN (1-92): 3.02e-34: 125: 34.78		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		661388 S10A2_HUMAN (2-95): 5.21e-32: 109: 40.43		TRI11_HUMAN (59-404): 1.13e-49: 179: 12.75
+	Hs
		301640 S10AB_HUMAN (2-92): 1.47e-35: 118: 40.66		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		416426 S10A9_HUMAN (1-91): 4.22e-31: 107: 36.96		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		1206192 HORN_HUMAN (1-92): 3.02e-34: 125: 34.78		TRIM6_HUMAN (56-403): 5.03e-39: 150: 12.97
+	Hs
		416677 S10A6_HUMAN (3-91): 5.01e-26: 93.8: 34.83		TRI11_HUMAN (59-404): 1.13e-49: 179: 12.75
+	Hs
		301543 S10A9_HUMAN (1-91): 4.22e-31: 107: 36.96		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		301707 S10AA_HUMAN (2-89): 2.29e-30: 104: 44.32		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		396734 S10A8_HUMAN (1-95): 5.49e-28: 98.8: 34.74		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		678448 S10A7_HUMAN (2-93): 2.88e-21: 81.8: 26.60		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		380815 S100B_HUMAN (1-92): 1.7e-31: 107: 50.00		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84
+	Hs
		707381 S10A3_HUMAN (3-93): 6.58e-30: 103: 32.97		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84