HitPredict

Interactor 1: EPHA1 (P21709)
Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)
Gene: EPHA1

Interactor 2: LRRC1 (Q9BTT6)
Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein)
Gene: LRRC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	LRR_8~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 976 Hs			1 524
+	Hs
		1147411 EPHA7_HUMAN (2-975): 0: 1125: 43.22		ERBIN_HUMAN (177-523): 1.34e-46: 177: 23.78
+	Hs
		1122235 EPHA7_HUMAN (2-975): 0: 1125: 43.22		SCRIB_HUMAN (209-522): 2.89e-45: 173: 21.45
+	Hs
		932119 EPHA4_HUMAN (5-975): 0: 1110: 43.50		ERBIN_HUMAN (177-523): 1.34e-46: 177: 23.78
+	Hs
		931882 EPHA5_HUMAN (3-975): 0: 1109: 41.71		ERBIN_HUMAN (177-523): 1.34e-46: 177: 23.78
+	Hs
		710831 EPHB2_HUMAN (27-975): 0: 1109: 40.81		SCRIB_HUMAN (209-522): 2.89e-45: 173: 21.45
+	Hs
		710651 EPHA3_HUMAN (22-975): 0: 1100: 42.49		ERBIN_HUMAN (177-523): 1.34e-46: 177: 23.78
+	Hs
		710440 EPHA2_HUMAN (24-976): 0: 1053: 49.90		ERBIN_HUMAN (177-523): 1.34e-46: 177: 23.78
+	Hs
		710238 EPHA2_HUMAN (24-976): 0: 1053: 49.90		SCRIB_HUMAN (209-522): 2.89e-45: 173: 21.45
+	Hs
		710453 EPHA2_HUMAN (24-976): 0: 1053: 49.90		LRRC1_HUMAN (278-522): 1.44e-21: 99: 17.41
+	At
		87903 Y5182_ARATH (346-915): 3.8e-151: 471: 16.12		RGI3_ARATH (3-465): 7.61e-69: 241: 24.95
+	Hs
		720306 UFO_HUMAN (274-914): 3.8e-156: 485: 25.11		ERBIN_HUMAN (177-523): 1.34e-46: 177: 23.78
+	Hs
		720218 UFO_HUMAN (274-914): 3.8e-156: 485: 25.11		SCRIB_HUMAN (209-522): 2.89e-45: 173: 21.45
+	At
		88676 NIK2_ARATH (341-920): 2.38e-155: 474: 16.02		GSO1_ARATH (134-522): 1.15e-40: 159: 19.50
+	At
		1342322 NIK2_ARATH (341-920): 2.38e-155: 474: 16.02		PXC2_ARATH (5-262): 7.08e-37: 147: 24.76
+	At
		1250982 NIK2_ARATH (341-920): 2.38e-155: 474: 16.02		ERL2_ARATH (3-298): 1.07e-35: 144: 20.00
+	At
		87925 Y5182_ARATH (346-915): 3.8e-151: 471: 16.12		PXC2_ARATH (5-262): 7.08e-37: 147: 24.76
+	At
		87930 Y5182_ARATH (346-915): 3.8e-151: 471: 16.12		CLV1_ARATH (14-176): 1.27e-24: 110: 25.15
+	Hs
		720327 UFO_HUMAN (274-914): 3.8e-156: 485: 25.11		LRC40_HUMAN (13-351): 4.58e-17: 86.3: 23.78
+	At
		87908 Y5182_ARATH (346-915): 3.8e-151: 471: 16.12		BAME1_ARATH (366-521): 5.63e-15: 80: 9.88
+	At
		87905 Y5182_ARATH (346-915): 3.8e-151: 471: 16.12		Y4361_ARATH (143-390): 2.64e-10: 65.5: 33.33