Interactor 1: DNMT1 (P26358)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)
Gene: DNMT1

Interactor 2: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29955894, 22055183, 21670149
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BAH~PHD
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1616
Hs

1 835
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024