HitPredict

Interactor 1: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Interactor 2: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1342 Hs			1 444
+	Hs
		457229 ERBB3_HUMAN (1-1342): 0: 1390: 100.00		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		411030 ERBB2_HUMAN (25-1222): 0: 1075: 39.95		TBB6_HUMAN (1-432): 0: 715: 86.81
+	Hs
		362607 EGFR_HUMAN (18-1211): 0: 1060: 40.65		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		363117 EGFR_HUMAN (18-1211): 0: 1060: 40.65		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		363241 EGFR_HUMAN (18-1211): 0: 1060: 40.65		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		363262 EGFR_HUMAN (18-1211): 0: 1060: 40.65		TBB2A_HUMAN (1-430): 0: 716: 90.00
+	Hs
		362569 EGFR_HUMAN (18-1211): 0: 1060: 40.65		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		363800 EGFR_HUMAN (18-1211): 0: 1060: 40.65		TBB6_HUMAN (1-432): 0: 715: 86.81
+	Hs
		1034331 ROR2_HUMAN (491-1088): 8.52e-118: 393: 20.22		TBB6_HUMAN (1-432): 0: 715: 86.81
+	Hs
		457332 EPHA4_HUMAN (656-996): 1.23e-103: 355: 27.79		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		932054 EPHA4_HUMAN (656-996): 1.23e-103: 355: 27.79		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		932127 EPHA4_HUMAN (656-996): 1.23e-103: 355: 27.79		TBB2B_HUMAN (1-430): 0: 719: 90.23
+	Hs
		408010 EPHA4_HUMAN (656-996): 1.23e-103: 355: 27.79		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		932126 EPHA4_HUMAN (656-996): 1.23e-103: 355: 27.79		TBB6_HUMAN (1-432): 0: 715: 86.81
+	Gg
		98959 KSYK_CHICK (715-958): 2.01e-43: 170: 36.80		TBB7_CHICK (1-429): 0: 720: 89.74
+	Hs
		439616 INSR_HUMAN (330-650): 2.92e-23: 109: 17.30		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		465633 IGF1R_HUMAN (330-644): 8.95e-24: 111: 21.34		TBB6_HUMAN (1-432): 0: 715: 86.81
+	Hs
		572922 INSRR_HUMAN (330-644): 1.2e-16: 88.3: 14.55		TBB3_HUMAN (1-442): 0: 719: 86.43