HitPredict

Interactor 1: KRA59 (P26371)
Keratin-associated protein 5-9 (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (Keratin-associated protein 5.9) (UHS keratin A) (UHS KerA) (Ultrahigh sulfur keratin-associated protein 5.9)
Gene: KRTAP5-9

Interactor 2: DOCK2 (Q92608)
Dedicator of cytokinesis protein 2
Gene: DOCK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 169 Hs			1 1830
+	Hs
		1216363 KRA13_HUMAN (8-166): 8.07e-21: 85.5: 26.25		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		1154498 TEN4_HUMAN (2-167): 1.55e-17: 80.9: 19.51		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		889850 KR109_HUMAN (39-168): 9.93e-17: 77.1: 26.14		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		888949 KR103_HUMAN (22-166): 2.09e-16: 75.1: 26.12		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		991635 KRA11_HUMAN (31-167): 3.12e-15: 71.3: 30.44		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		889608 KR108_HUMAN (26-165): 4.36e-14: 69.4: 28.87		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		1267941 KRA92_HUMAN (47-166): 3.82e-14: 68.2: 34.71		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		888752 KR101_HUMAN (7-162): 7.55e-13: 66.3: 28.30		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		1267940 KRA93_HUMAN (63-166): 1.18e-12: 64: 29.81		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		1267939 KRA94_HUMAN (62-166): 1.31e-11: 60.9: 31.19		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		889351 KR107_HUMAN (26-165): 1.87e-09: 57: 25.30		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		1267942 KRA42_HUMAN (11-107): 9.97e-10: 55.5: 24.24		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Hs
		888604 KR123_HUMAN (6-98): 8.5e-10: 54.7: 23.16		DOCK2_HUMAN (1-1830): 0: 2494: 100.00
+	Dm
		246962 TENM_DROME (47-168): 1.59e-09: 57.8: 20.80		Q9VAS8_DROME (4-1690): 0: 1801: 36.61
+	Dm
		247090 TENM_DROME (47-168): 1.59e-09: 57.8: 20.80		Q9VM04_DROME (315-930): 1.51e-117: 416: 16.81
+	Dm
		247136 TENM_DROME (47-168): 1.59e-09: 57.8: 20.80		Q9VPI9_DROME (322-929): 6.48e-51: 201: 13.81