Protein: RRP4
Exosome complex component RRP4 (Ribosomal RNA-processing protein 4)

Gene: RRP4
Organism: Saccharomyces cerevisiae S288C
Interactions: 102
UniProt ID: P38792

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

754968

RRP41
Exosome complex component SKI6

9

20

Small-scale

0.971

High

754976

RRP46
Exosome complex component RRP46

9

20

Small-scale

0.970

High

754995

RRP45
Exosome complex component RRP45

7

20

Small-scale

0.962

High

630193

RRP43
Exosome complex component RRP43

6

0

Small-scale

0.895

High

755006

RRP40
Exosome complex component RRP40

3

7

High-throughput

0.855

High

754979

MPP6
M-phase phosphoprotein 6 homolog

4

0

Small-scale

0.853

High

754972

MTR3
Exosome complex component MTR3

4

0

Small-scale

0.848

High

755005

RRP44
Exosome complex exonuclease DIS3

14

13

Small-scale

0.761

High

755012

RRP6
Exosome complex exonuclease RRP6

14

8

Small-scale

0.760

High

754980

CSL4
Exosome complex component CSL4

9

5

Small-scale

0.751

High

755007

SKI7
Superkiller protein 7

7

3

Small-scale

0.745

High

754993

RRP5
rRNA biogenesis protein RRP5

2

1

High-throughput

0.737

High

755015

RRP42
Exosome complex component RRP42

5

20

Small-scale

0.714

High

754957

LRP1
Exosome complex protein LRP1

6

0

Small-scale

0.702

High

748600

ENP1
Essential nuclear protein 1

3

1

High-throughput

0.640

High

754990

DHR1
Probable ATP-dependent RNA helicase DHR1

3

2

High-throughput

0.640

High

754978

NRD1
Protein NRD1

3

0

Small-scale

0.628

High

571891

SKI3
Superkiller protein 3

2

0

High-throughput

0.588

High

634592

KRR1
KRR1 small subunit processome component

2

1

High-throughput

0.584

High

754967

UTP10
U3 small nucleolar RNA-associated protein 10

2

1

High-throughput

0.584

High

754969

MTR4
ATP-dependent RNA helicase DOB1

2

9

Small-scale

0.584

High

754992

UTP14
U3 small nucleolar RNA-associated protein 14

2

1

High-throughput

0.584

High

755001

NOC4
Nucleolar complex protein 4

2

2

High-throughput

0.584

High

754987

IMA1
Importin subunit alpha

2

0

High-throughput

0.576

High

491142

HSP71
Heat shock protein SSA1

2

2

Small-scale

0.571

High

493905

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.552

High

754962

SSB2
Ribosome-associated molecular chaperone SSB2

2

3

High-throughput

0.552

High

754958

UTP9
U3 small nucleolar RNA-associated protein 9

2

0

High-throughput

0.547

High

754986

SKI8
Antiviral protein SKI8

1

3

High-throughput

0.541

High

511228

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.536

High

754399

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.536

High

383132

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

405609

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

407034

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

407902

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

408352

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

630482

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.479

High

631864

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

635575

PWP2
Periodic tryptophan protein 2

1

2

High-throughput

0.479

High

645431

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

707083

DCA13
Protein SOF1

1

5

High-throughput

0.479

High

715926

UTP20
U3 small nucleolar RNA-associated protein 20

1

1

High-throughput

0.479

High

716179

SKI2
Antiviral helicase SKI2

1

9

High-throughput

0.479

High

728234

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.479

High

754960

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

Small-scale

0.479

High

754961

UTP7
U3 small nucleolar RNA-associated protein 7

1

3

High-throughput

0.479

High

754963

UTP18
U3 small nucleolar RNA-associated protein 18

1

1

High-throughput

0.479

High

754970

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

1

High-throughput

0.479

High

754971

NOL10
Ribosome biogenesis protein ENP2

1

1

High-throughput

0.479

High

754975

UTP22
U3 small nucleolar RNA-associated protein 22

1

1

High-throughput

0.479

High

754981

NAT10
RNA cytidine acetyltransferase

1

1

High-throughput

0.479

High

754983

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

2

High-throughput

0.479

High

754984

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

754988

UTP17
NET1-associated nuclear protein 1

1

7

High-throughput

0.479

High

754989

UTP5
U3 small nucleolar RNA-associated protein 5

1

4

High-throughput

0.479

High

754991

UTP15
U3 small nucleolar RNA-associated protein 15

1

4

High-throughput

0.479

High

754996

UTP13
U3 small nucleolar RNA-associated protein 13

1

4

High-throughput

0.479

High

754997

UTP21
U3 small nucleolar RNA-associated protein 21

1

6

High-throughput

0.479

High

754998

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

1

High-throughput

0.479

High

755000

RRP9
Ribosomal RNA-processing protein 9

1

5

High-throughput

0.479

High

755002

BFR2
Protein BFR2

1

1

High-throughput

0.479

High

755003

UTP4
U3 small nucleolar RNA-associated protein 4

1

4

High-throughput

0.479

High

755004

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

1

High-throughput

0.479

High

755009

BMS1
Ribosome biogenesis protein BMS1

1

1

High-throughput

0.479

High

755010

FCF2
rRNA-processing protein FCF2

1

1

High-throughput

0.479

High

755014

UTP12
U3 small nucleolar RNA-associated protein 12

1

3

High-throughput

0.479

High

755016

NOP56
Nucleolar protein 56

1

3

High-throughput

0.479

High

755017

NOP58
Nucleolar protein 58

1

3

High-throughput

0.479

High

755019

NOP14
Nucleolar complex protein 14

1

1

High-throughput

0.479

High

141318

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

480091

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

558044

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

628024

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

662154

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688229

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

711033

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

729901

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

754964

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

754965

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

754966

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

754977

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

754982

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

754985

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

754994

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

755008

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

755011

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

755013

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

755018

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

694649

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

480659

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

706260

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

752438

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

366253

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

754974

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

754999

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.426

High

489672

MPPB
Mitochondrial-processing peptidase subunit beta

2

0

High-throughput

0.307

High

730555

MYO3
Myosin-3

1

0

High-throughput

0.269

Low

350878

YPT1
GTP-binding protein YPT1

1

0

Small-scale

0.249

Low

754973

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

424505

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

450432

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.232

Low

754959

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024