Protein: IDHP
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)

Gene: IDHP, IDP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: P21954

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004450 - isocitrate dehydrogenase (NADP+) activity
GO:0005739 - mitochondrion
GO:0006097 - glyoxylate cycle
GO:0006099 - tricarboxylic acid cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

642157

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

1

High-throughput

0.628

High

642124

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

4

High-throughput

0.618

High

642125

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

5

High-throughput

0.618

High

510195

HSP77
Import motor subunit, mitochondrial

2

4

High-throughput

0.584

High

578850

HSC82
ATP-dependent molecular chaperone HSC82

2

2

High-throughput

0.584

High

642151

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

642155

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

642120

SIS1
Protein SIS1

2

1

High-throughput

0.521

High

364925

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.513

High

555226

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.513

High

642147

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.513

High

642159

YP109
ABC1 family protein YPL109C, mitochondrial

1

0

High-throughput

0.513

High

642143

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.504

High

399795

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.486

High

366928

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.479

High

484722

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

594879

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

604900

MDHM
Malate dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

622318

ACON
Aconitate hydratase, mitochondrial

1

3

High-throughput

0.479

High

635927

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

642130

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.479

High

642131

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

642132

PREP
Presequence protease, mitochondrial

1

1

High-throughput

0.479

High

642134

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.479

High

642142

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

1

High-throughput

0.479

High

642150

ETFB
Probable electron transfer flavoprotein subunit beta

1

1

High-throughput

0.479

High

642152

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

642162

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

2

High-throughput

0.479

High

642153

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

High-throughput

0.470

High

439090

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

452630

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.458

High

456330

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.458

High

626584

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.458

High

642119

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.458

High

642121

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.458

High

642123

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

High-throughput

0.458

High

642129

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.458

High

642137

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

642148

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

642156

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

642161

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

597035

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.457

High

571343

CPYI
Carboxypeptidase Y inhibitor

1

2

Small-scale

0.437

High

642126

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

642127

HS104
Heat shock protein 104

1

3

High-throughput

0.437

High

642128

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

642145

TM108
Protein TMA108

1

1

High-throughput

0.437

High

543818

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.407

High

642118

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.407

High

642135

RS3A1
Small ribosomal subunit protein eS1A

2

0

High-throughput

0.318

High

617847

DDR48
Stress protein DDR48

2

0

High-throughput

0.313

High

434826

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

441705

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

454877

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

513457

RL1A
Large ribosomal subunit protein uL1A

1

0

High-throughput

0.249

Low

642122

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.249

Low

642133

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

642136

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

642138

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

642140

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

642141

ARB1
ABC transporter ATP-binding protein ARB1

1

0

Small-scale

0.249

Low

642144

RIO2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.249

Low

642146

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

642154

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

642158

MLP1
Protein MLP1

1

0

High-throughput

0.249

Low

642160

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

642163

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

403354

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.232

Low

444420

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.232

Low

531604

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.232

Low

642139

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.232

Low

642149

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025