HitPredict

Interactor 1: KCNA3 (P22001)
Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3)
Gene: KCNA3

Interactor 2: KCD12 (Q96CX2)
BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain)
Gene: KCTD12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	39231216
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB_2~BTB_2
Common GO terms	GO:0051260 - protein homooligomerization
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 575 Hs			1 325
+	Hs
		642827 KCNA3_HUMAN (1-575): 0: 556: 100.00		KCNA1_HUMAN (1-222): 6.53e-51: 177: 15.49
+	Hs
		595030 KCNA3_HUMAN (1-575): 0: 556: 100.00		KCNA2_HUMAN (1-238): 9.39e-49: 171: 15.66
+	Mm
		595025 KCNA1_MOUSE (53-575): 2.37e-144: 428: 69.58		BACD1_MOUSE (1-265): 1.81e-73: 231: 21.21
+	Hs
		595040 KCNA2_HUMAN (53-575): 1.78e-148: 438: 70.97		KCNA1_HUMAN (1-222): 6.53e-51: 177: 15.49
+	Mm
		595023 KCNA2_MOUSE (53-575): 9.91e-149: 439: 70.97		KCNA1_MOUSE (1-222): 1.02e-49: 174: 15.49
+	Hs
		595028 KCNA2_HUMAN (53-575): 1.78e-148: 438: 70.97		KCNA2_HUMAN (1-238): 9.39e-49: 171: 15.66
+	Rn
		522321 KCNA1_RAT (53-575): 6.38e-145: 429: 69.96		KCNA1_RAT (1-222): 2.62e-50: 176: 15.49
+	Hs
		1067216 KCNA1_HUMAN (53-575): 3.35e-144: 427: 69.39		KCNA1_HUMAN (1-222): 6.53e-51: 177: 15.49
+	Hs
		648768 KCNA4_HUMAN (80-575): 4.67e-141: 425: 66.86		KCNA1_HUMAN (1-222): 6.53e-51: 177: 15.49
+	Hs
		595031 KCNA4_HUMAN (80-575): 4.67e-141: 425: 66.86		KCNA2_HUMAN (1-238): 9.39e-49: 171: 15.66
+	Hs
		595032 KCNA5_HUMAN (13-508): 1.07e-139: 420: 64.02		KCNA2_HUMAN (1-238): 9.39e-49: 171: 15.66
+	Hs
		648844 KCNA5_HUMAN (13-508): 1.07e-139: 420: 64.02		KCND3_HUMAN (3-177): 7.45e-44: 161: 19.02
+	Hs
		1067219 KCNA1_HUMAN (53-575): 3.35e-144: 427: 69.39		KCNRG_HUMAN (31-230): 1.78e-43: 152: 28.50
+	Hs
		1131514 KCNB1_HUMAN (75-538): 3.62e-129: 400: 32.25		KCNS3_HUMAN (28-238): 1.57e-51: 179: 17.12
+	Hs
		648784 KCNA4_HUMAN (80-575): 4.67e-141: 425: 66.86		KCNRG_HUMAN (31-230): 1.78e-43: 152: 28.50
+	Hs
		1131500 KCNB1_HUMAN (75-538): 3.62e-129: 400: 32.25		KCNB1_HUMAN (10-184): 3.39e-42: 157: 19.47
+	Hs
		1131512 KCNB1_HUMAN (75-538): 3.62e-129: 400: 32.25		KCNB2_HUMAN (3-184): 2.17e-41: 155: 15.46
+	Mm
		64323 KCNB1_MOUSE (75-537): 1.04e-128: 399: 32.11		KCNB2_MOUSE (3-184): 7.6e-42: 156: 15.98