HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: MYCPP (Q7Z401)
C-myc promoter-binding protein (DENN domain-containing protein 4A)
Gene: DENND4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	17353931, 33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1863
+	Hs
		909741 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYCPP_HUMAN (1-1863): 0: 2589: 100.00
+	Hs
		927224 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYCPP_HUMAN (1-1863): 0: 2589: 100.00
+	Hs
		909665 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DEN4C_HUMAN (1-1863): 0: 2345: 47.59
+	Hs
		646988 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DEN4C_HUMAN (1-1863): 0: 2345: 47.59
+	Hs
		927152 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		DEN4C_HUMAN (1-1863): 0: 2345: 47.59
+	Hs
		309464 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MTMR5_HUMAN (211-824): 1.49e-157: 532: 21.65
+	Mm
		926821 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MTMR5_MOUSE (211-824): 2.91e-157: 532: 23.14
+	Hs
		309444 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MTMR5_HUMAN (211-824): 1.49e-157: 532: 21.65
+	Hs
		909848 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DEN1A_HUMAN (197-748): 3.75e-113: 387: 17.81
+	Hs
		647133 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DEN1A_HUMAN (197-748): 3.75e-113: 387: 17.81
+	Hs
		927335 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		DEN1A_HUMAN (197-748): 3.75e-113: 387: 17.81
+	Hs
		646993 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DEN2C_HUMAN (202-677): 1.17e-103: 358: 19.96
+	Hs
		909687 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DEN1B_HUMAN (209-713): 1.07e-101: 348: 18.93
+	Mm
		926828 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MADD_MOUSE (201-630): 1.4e-96: 348: 21.63
+	Hs
		647009 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DEN1B_HUMAN (209-713): 1.07e-101: 348: 18.93
+	Hs
		909436 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DEN2B_HUMAN (202-677): 7.85e-96: 339: 19.80
+	Hs
		927176 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		DEN1B_HUMAN (209-713): 1.07e-101: 348: 18.93
+	Hs
		927349 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MADD_HUMAN (201-630): 7.32e-96: 346: 21.63
+	Hs
		646791 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DEN2B_HUMAN (202-677): 7.85e-96: 339: 19.80
+	Hs
		926916 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		DEN2B_HUMAN (202-677): 7.85e-96: 339: 19.80