HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28024152
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 522
+	Hs
		584921 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		RO52_HUMAN (64-403): 5.77e-45: 166: 14.97
+	Hs
		646884 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		909675 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		TRI68_HUMAN (60-385): 1.41e-42: 160: 12.91
+	Hs
		927038 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		301628 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		584924 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		RO52_HUMAN (64-403): 5.77e-45: 166: 14.97
+	Hs
		301746 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		647252 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		TRIM4_HUMAN (61-336): 6.36e-43: 161: 12.90
+	Hs
		909495 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59
+	Hs
		647250 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		TRI31_HUMAN (58-334): 3.02e-35: 138: 15.00
+	Hs
		927527 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		RNF41_HUMAN (55-177): 2.33e-17: 84.9: 33.33
+	Hs
		684032 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		684114 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		TRI68_HUMAN (60-385): 1.41e-42: 160: 12.91
+	Zm
		80623 B6U284_MAIZE (1-243): 2.35e-143: 403: 59.92		K7UZW2_MAIZE (61-179): 3.76e-11: 67.9: 24.03
+	Mm
		926859 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		LNX2_MOUSE (58-183): 4.87e-12: 70.6: 22.66
+	Mm
		250606 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		LNX1_MOUSE (51-183): 2.1e-11: 68.7: 19.55
+	Mm
		250609 1433T_MOUSE (1-245): 2.96e-141: 397: 99.59		LNX1_MOUSE (51-183): 2.1e-11: 68.7: 19.55
+	Hs
		927328 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84
+	Mm
		250656 1433B_MOUSE (1-242): 2.84e-124: 354: 80.99		LNX1_MOUSE (51-183): 2.1e-11: 68.7: 19.55
+	Hs
		684204 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		LNX2_HUMAN (58-183): 1.56e-11: 69.1: 21.88