Interactor 1: TBKB1 (A7MCY6)
TANK-binding kinase 1-binding protein 1 (TBK1-binding protein 1)
Gene: TBKBP1

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 21903422, 17568778, 27035970, 14743216, 30420664, 29395067, 32707033, 36736316, 23286385, 21931555
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0007249 - canonical NF-kappaB signal transduction
GO:0051607 - defense response to virus
GO:0060337 - type I interferon-mediated signaling pathway
GO:1902554 - serine/threonine protein kinase complex
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 615
Hs

1 729
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024