Protein: ODPX
Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)

Gene: ODPX, PDHX
Organism: Homo sapiens
Interactions: 91
UniProt ID: O00330

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate
GO:0016746 - acyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

126212

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

6

12

Small-scale

0.950

High

126214

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

4

8

Small-scale

0.892

High

126213

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

2

13

Small-scale

0.767

High

126259

HSC20
Iron-sulfur cluster co-chaperone protein HscB

3

2

Small-scale

0.653

High

126245

PDK1
[Pyruvate dehydrogenase

3

9

High-throughput

0.640

High

126231

IF2M
Translation initiation factor IF-2, mitochondrial

2

9

High-throughput

0.628

High

126247

PDK3
[Pyruvate dehydrogenase

2

9

High-throughput

0.628

High

126211

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

11

High-throughput

0.618

High

126228

STA5A
Signal transducer and activator of transcription 5A

2

3

High-throughput

0.574

High

126242

FOXD4
Forkhead box protein D4

2

1

High-throughput

0.574

High

126251

PPCEL
Prolyl endopeptidase-like

2

1

High-throughput

0.574

High

126240

EP300
Histone acetyltransferase p300

1

6

Small-scale

0.561

High

126290

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

5

High-throughput

0.550

High

126286

HECD1
E3 ubiquitin-protein ligase HECTD1

2

7

High-throughput

0.533

High

126246

PDK2
[Pyruvate dehydrogenase

1

9

Small-scale

0.501

High

126219

MIF
Macrophage migration inhibitory factor

1

1

High-throughput

0.489

High

126233

STA5B
Signal transducer and activator of transcription 5B

1

3

High-throughput

0.489

High

126250

AAK1
AP2-associated protein kinase 1

1

1

High-throughput

0.489

High

126282

HDAC6
Histone deacetylase 6

1

3

High-throughput

0.489

High

126267

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

Small-scale

0.481

High

126205

MPPB
Mitochondrial-processing peptidase subunit beta

1

9

High-throughput

0.479

High

126206

RF1M
Peptide chain release factor 1, mitochondrial

1

10

High-throughput

0.479

High

126207

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

4

High-throughput

0.479

High

126208

GCR
Glucocorticoid receptor

1

7

Small-scale

0.479

High

126226

MDHM
Malate dehydrogenase, mitochondrial

1

4

High-throughput

0.479

High

126230

EFTS
Elongation factor Ts, mitochondrial

1

3

High-throughput

0.479

High

126232

EFTU
Elongation factor Tu, mitochondrial

1

6

High-throughput

0.479

High

126241

MPPA
Mitochondrial-processing peptidase subunit alpha

1

9

High-throughput

0.479

High

126249

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

3

High-throughput

0.479

High

126263

FAKD4
FAST kinase domain-containing protein 4

1

9

High-throughput

0.479

High

126264

RRFM
Ribosome-recycling factor, mitochondrial

1

3

High-throughput

0.479

High

126265

EFGM
Elongation factor G, mitochondrial

1

8

High-throughput

0.479

High

126269

TACO1
Translational activator of cytochrome c oxidase 1

1

3

High-throughput

0.479

High

126271

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

3

High-throughput

0.479

High

126274

RT26
Small ribosomal subunit protein mS26

1

3

High-throughput

0.479

High

126275

MTG2
Mitochondrial ribosome-associated GTPase 2

1

6

High-throughput

0.479

High

126277

MET17
Ribosome assembly protein METTL17, mitochondrial

1

3

High-throughput

0.479

High

126278

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

3

High-throughput

0.479

High

126280

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

4

High-throughput

0.479

High

126281

MRES1
Mitochondrial transcription rescue factor 1

1

3

High-throughput

0.479

High

126283

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

10

High-throughput

0.479

High

126288

RM11
Large ribosomal subunit protein uL11m

1

3

High-throughput

0.479

High

126289

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

Small-scale

0.479

High

126203

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

5

High-throughput

0.457

High

81542

B7Z207
Protein-serine/threonine kinase

1

9

High-throughput

0.445

High

126216

ACTN1
Alpha-actinin-1

1

2

High-throughput

0.439

High

120193

RHOD
Rho-related GTP-binding protein RhoD

1

8

High-throughput

0.437

High

126204

TMPS2
Transmembrane protease serine 2

1

4

High-throughput

0.437

High

126217

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.437

High

126218

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.437

High

126220

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.437

High

126221

CAN2
Calpain-2 catalytic subunit

1

1

High-throughput

0.437

High

126222

LEG3
Galectin-3

1

3

Small-scale

0.437

High

126223

BRD2
Bromodomain-containing protein 2

1

7

High-throughput

0.437

High

126224

MERL
Merlin

1

3

High-throughput

0.437

High

126227

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

126234

RHOA
Transforming protein RhoA

1

8

High-throughput

0.437

High

126235

RND3
Rho-related GTP-binding protein RhoE

1

14

High-throughput

0.437

High

126236

RHOB
Rho-related GTP-binding protein RhoB

1

8

High-throughput

0.437

High

126237

RAC1
Ras-related C3 botulinum toxin substrate 1

1

6

High-throughput

0.437

High

126238

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.437

High

126243

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

5

High-throughput

0.437

High

126244

NDF1
Neurogenic differentiation factor 1

1

2

Small-scale

0.437

High

126248

RHOH
Rho-related GTP-binding protein RhoH

1

11

High-throughput

0.437

High

126253

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.437

High

126255

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

126257

RHOU
Rho-related GTP-binding protein RhoU

1

11

High-throughput

0.437

High

126258

TM11B
Transmembrane protease serine 11B

1

4

High-throughput

0.437

High

126260

MILK2
MICAL-like protein 2

1

4

High-throughput

0.437

High

126262

RND1
Rho-related GTP-binding protein Rho6

1

13

High-throughput

0.437

High

126268

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.437

High

126270

CQ080
Mitochondrial nucleoid-associated protein 1

1

3

High-throughput

0.437

High

126276

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

126279

TMPS4
Transmembrane protease serine 4

1

4

High-throughput

0.437

High

126284

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

126287

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.437

High

126215

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.417

High

126209

JUN
Transcription factor Jun

1

3

High-throughput

0.407

High

126229

CNDD3
Condensin-2 complex subunit D3

1

3

High-throughput

0.407

High

126252

CP135
Centrosomal protein of 135 kDa

1

9

High-throughput

0.407

High

126256

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

3

High-throughput

0.407

High

126261

POC5
Centrosomal protein POC5

1

3

High-throughput

0.407

High

126266

CK5P2
CDK5 regulatory subunit-associated protein 2

1

9

High-throughput

0.407

High

126273

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

3

High-throughput

0.407

High

126254

ATRAP
Type-1 angiotensin II receptor-associated protein

3

0

High-throughput

0.350

High

126285

CIDEB
Lipid transferase CIDEB

2

0

High-throughput

0.316

High

126239

EWS
RNA-binding protein EWS

1

0

High-throughput

0.282

High

48174

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.249

Low

126225

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.249

Low

126272

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low

126210

S10A9
Protein S100-A9

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024