HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: ARC1A (Q92747)
Actin-related protein 2/3 complex subunit 1A (SOP2-like protein)
Gene: ARPC1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0035861 - site of double-strand break
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 370
+	Hs
		168735 RFA1_HUMAN (1-616): 0: 781: 100.00		ARC1B_HUMAN (1-369): 2.59e-83: 259: 68.10
+	Hs
		651925 RFA1_HUMAN (1-616): 0: 781: 100.00		SNR40_HUMAN (129-369): 1.6e-45: 161: 14.92
+	Hs
		650859 RFA1_HUMAN (1-616): 0: 781: 100.00		WDR5_HUMAN (175-363): 2.8e-38: 141: 14.87
+	Hs
		650793 RFA1_HUMAN (1-616): 0: 781: 100.00		SEC13_HUMAN (91-362): 4.51e-11: 65.2: 13.81
+	Hs
		652407 RFA1_HUMAN (1-616): 0: 781: 100.00		NLE1_HUMAN (278-367): 3.77e-09: 59.8: 11.58