Protein: DUS26
Dual specificity protein phosphatase 26 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase SKRP3) (Low-molecular-mass dual-specificity phosphatase 4) (DSP-4) (LDP-4) (Mitogen-activated protein kinase phosphatase 8) (MAP kinase phosphatase 8) (MKP-8) (Novel amplified gene in thyroid anaplastic cancer)

Gene: DUS26, DUSP26
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q9BV47

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0002039 - p53 binding
GO:0004721 - phosphoprotein phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

909169

NEK4
Serine/threonine-protein kinase Nek4

1

5

High-throughput

0.691

High

1158175

MK14
Mitogen-activated protein kinase 14

1

20

Small-scale

0.691

High

1331603

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

2

11

High-throughput

0.675

High

710456

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.625

High

1147419

EPHA7
Ephrin type-A receptor 7

1

19

High-throughput

0.625

High

659057

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

1

High-throughput

0.618

High

691839

MK03
Mitogen-activated protein kinase 3

1

20

Small-scale

0.618

High

1414911

DUS26
Dual specificity protein phosphatase 26

1

17

High-throughput

0.618

High

1196311

GRAP1
GRIP1-associated protein 1

2

4

High-throughput

0.606

High

1414913

CAR10
Caspase recruitment domain-containing protein 10

2

6

High-throughput

0.606

High

326011

UBR5
E3 ubiquitin-protein ligase UBR5

2

2

High-throughput

0.584

High

1277621

K1C27
Keratin, type I cytoskeletal 27

2

0

High-throughput

0.580

High

1095782

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

10

High-throughput

0.573

High

414533

P53
Cellular tumor antigen p53

1

0

Small-scale

0.571

High

1414918

HSF4
Heat shock factor protein 4

1

0

Small-scale

0.561

High

65155

GG6L9
Golgin subfamily A member 6-like protein 9

2

7

High-throughput

0.553

High

465634

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.541

High

1414921

KIF3A
Kinesin-like protein KIF3A

1

4

Small-scale

0.506

High

464047

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.494

High

1101771

PTK7
Inactive tyrosine-protein kinase 7

1

10

High-throughput

0.494

High

176707

PUR4
Phosphoribosylformylglycinamidine synthase

1

1

High-throughput

0.479

High

220978

XPOT
Exportin-T

1

6

High-throughput

0.479

High

289679

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

5

High-throughput

0.479

High

343036

HERC2
E3 ubiquitin-protein ligase HERC2

1

1

High-throughput

0.479

High

618285

CADH2
Cadherin-2

1

2

Small-scale

0.479

High

765002

CTNB1
Catenin beta-1

1

2

Small-scale

0.479

High

841911

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

9

High-throughput

0.479

High

888980

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.479

High

907561

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

5

High-throughput

0.479

High

992640

IF5A1
Eukaryotic translation initiation factor 5A-1

1

4

High-throughput

0.479

High

1060482

DPOE1
DNA polymerase epsilon catalytic subunit A

1

3

High-throughput

0.479

High

1130170

SMC1A
Structural maintenance of chromosomes protein 1A

1

2

High-throughput

0.479

High

1131369

GANAB
Neutral alpha-glucosidase AB

1

3

High-throughput

0.479

High

1241646

ANM9
Protein arginine N-methyltransferase 9

1

1

High-throughput

0.479

High

1241772

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

High-throughput

0.479

High

1311164

UBR2
E3 ubiquitin-protein ligase UBR2

1

1

High-throughput

0.479

High

1406614

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.479

High

1414912

DUS23
Dual specificity protein phosphatase 23

1

18

High-throughput

0.479

High

1414914

DCTP1
dCTP pyrophosphatase 1

1

1

High-throughput

0.479

High

1414916

FANCI
Fanconi anemia group I protein

1

1

High-throughput

0.479

High

1414917

GID8
Glucose-induced degradation protein 8 homolog

1

4

High-throughput

0.479

High

1414919

DICER
Endoribonuclease Dicer

1

8

High-throughput

0.479

High

1414922

DCAF1
DDB1- and CUL4-associated factor 1

1

1

High-throughput

0.479

High

71786

ZNF99
Zinc finger protein 99

1

0

High-throughput

0.458

High

693073

DPP4
Dipeptidyl peptidase 4

1

0

Small-scale

0.458

High

944551

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.458

High

1028369

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

1128468

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

0

High-throughput

0.458

High

1271125

TM10C
tRNA methyltransferase 10 homolog C

1

0

High-throughput

0.458

High

1414915

XPP1
Xaa-Pro aminopeptidase 1

1

0

High-throughput

0.458

High

1369527

KIFA3
Kinesin-associated protein 3

1

3

Small-scale

0.445

High

124470

HAX1
HCLS1-associated protein X-1

1

4

High-throughput

0.437

High

282064

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.437

High

335639

AGM1
Phosphoacetylglucosamine mutase

1

1

High-throughput

0.437

High

1083729

MPPA
Mitochondrial-processing peptidase subunit alpha

1

3

High-throughput

0.437

High

1210366

NU188
Nucleoporin NUP188

1

1

High-throughput

0.437

High

1356931

NU133
Nuclear pore complex protein Nup133

1

1

High-throughput

0.437

High

1365894

NU205
Nuclear pore complex protein Nup205

1

4

High-throughput

0.437

High

1385163

ATG2B
Autophagy-related protein 2 homolog B

1

2

High-throughput

0.437

High

1398826

DOCK7
Dedicator of cytokinesis protein 7

1

2

High-throughput

0.437

High

1414920

WIPI4
WD repeat domain phosphoinositide-interacting protein 4

1

2

High-throughput

0.437

High

1414923

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

6

High-throughput

0.437

High

1085277

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.249

Low

1395394

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025