Interactor 1: LET60 (P22981)
Ras protein let-60 (EC 3.6.5.2) (Abnormal cell lineage protein 34) (Lethal protein 60)
Gene: let-60
Interactor 2: KRAF1 (Q07292)
Raf homolog serine/threonine-protein kinase (EC 2.7.11.1) (Abnormal cell lineage protein 45)
Gene: lin-45
Species: Caenorhabditis elegans
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9674433 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~Ras, PK_Tyr_Ser-Thr~Ras, RBD~Ras |
| Common GO terms | GO:0002119 - nematode larval development GO:0007265 - Ras protein signal transduction GO:0022414 - reproductive process GO:0048477 - oogenesis |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
