HitPredict

Interactor 1: DC8L2 (P0C7V8)
DDB1- and CUL4-associated factor 8-like protein 2 (WD repeat-containing protein 42C)
Gene: DCAF8L2

Interactor 2: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 631 Hs			1 556
+	Hs
		573301 DCAF8_HUMAN (1-631): 8.69e-125: 383: 64.56		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		826701 DCAF8_HUMAN (1-631): 8.69e-125: 383: 64.56		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		473605 DC8L2_HUMAN (1-631): 7.02e-134: 407: 100.00		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		1135834 DCAF8_HUMAN (1-631): 8.69e-125: 383: 64.56		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		821253 DCAF8_HUMAN (1-631): 8.69e-125: 383: 64.56		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Hs
		573324 WDR82_HUMAN (213-543): 1.04e-63: 214: 20.72		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		573346 WDR5B_HUMAN (358-627): 6.66e-50: 178: 12.13		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		826727 WDR82_HUMAN (213-543): 1.04e-63: 214: 20.72		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		573406 FBXW7_HUMAN (118-390): 2.4e-44: 170: 15.94		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		196954 PRP4_HUMAN (316-618): 4.25e-45: 169: 10.58		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		573384 POC1B_HUMAN (106-349): 1.72e-39: 153: 15.66		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		1166712 WDR82_HUMAN (213-543): 1.04e-63: 214: 20.72		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		826748 WDR5B_HUMAN (358-627): 6.66e-50: 178: 12.13		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		821276 WDR82_HUMAN (213-543): 1.04e-63: 214: 20.72		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Hs
		826807 FBXW7_HUMAN (118-390): 2.4e-44: 170: 15.94		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		196973 PRP4_HUMAN (316-618): 4.25e-45: 169: 10.58		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		1202777 WDR5B_HUMAN (358-627): 6.66e-50: 178: 12.13		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		197078 PRP4_HUMAN (316-618): 4.25e-45: 169: 10.58		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		196971 PRP4_HUMAN (316-618): 4.25e-45: 169: 10.58		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Hs
		821326 POC1B_HUMAN (106-349): 1.72e-39: 153: 15.66		TCPE_HUMAN (4-530): 0: 550: 31.96