HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: RN149 (Q8NC42)
E3 ubiquitin-protein ligase RNF149 (EC 2.3.2.27) (DNA polymerase-transactivated protein 2) (RING finger protein 149) (RING-type E3 ubiquitin transferase RNF149)
Gene: RNF149

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36610398
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 400
+	Hs
		654590 CALX_HUMAN (1-592): 0: 786: 100.00		RN128_HUMAN (11-387): 1.62e-91: 283: 38.38
+	Hs
		654504 CALX_HUMAN (1-592): 0: 786: 100.00		GOLI_HUMAN (30-374): 2.45e-84: 264: 40.52
+	Hs
		654428 CALX_HUMAN (1-592): 0: 786: 100.00		RNF43_HUMAN (58-391): 1.15e-52: 189: 18.08
+	Hs
		654604 CALX_HUMAN (1-592): 0: 786: 100.00		ZNRF4_HUMAN (32-389): 1.03e-53: 185: 18.35
+	Hs
		654891 CALX_HUMAN (1-592): 0: 786: 100.00		AMFR_HUMAN (96-398): 5.47e-37: 143: 15.29
+	Hs
		653647 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		GOLI_HUMAN (30-374): 2.45e-84: 264: 40.52