Protein: DICH
SOX domain-containing protein dichaete (Protein fish-hook)

Gene: DICH, D
Organism: Drosophila melanogaster
Interactions: 70
UniProt ID: Q24533

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002168 - instar larval development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1174466

DICH
SOX domain-containing protein dichaete

4

19

Small-scale

0.884

High

1174467

HMG2
High mobility group protein DSP1

2

18

High-throughput

0.767

High

121514

M9PFG6
Sox21a, isoform B

2

20

High-throughput

0.754

High

593559

CF1A
POU domain protein CF1A

2

20

Small-scale

0.704

High

725830

PDM1
Protein nubbin

2

20

Small-scale

0.704

High

942041

OTP
Homeobox protein orthopedia

3

20

High-throughput

0.661

High

1174485

PDM2B
POU domain protein 2, isoform B

1

20

Small-scale

0.621

High

432405

SIM
Protein single-minded

2

18

Small-scale

0.600

High

652970

VND
Homeobox protein vnd

2

20

Small-scale

0.600

High

750532

FTZF1
Nuclear hormone receptor FTZ-F1

2

20

Small-scale

0.600

High

355859

O96660
Mothers against decapentaplegic homolog

2

20

High-throughput

0.594

High

647283

SUS
Protein suppressor of sable

2

2

High-throughput

0.594

High

1174469

Q7JR80
SD23764p

2

17

High-throughput

0.594

High

1174470

Q7KNM2
Dorsal interacting protein 4

2

10

High-throughput

0.594

High

1174477

Q961D1
Cyclin-K

2

7

High-throughput

0.594

High

1174479

Q9U8L5
Dorsocross1, isoform A

2

14

High-throughput

0.594

High

1174480

Q9V472
DLim1

2

20

High-throughput

0.594

High

1174483

Q9VJL7
IP01243p

2

10

High-throughput

0.594

High

1174490

FOXF
Forkhead box protein biniou

2

20

High-throughput

0.594

High

1174494

Q9VYG4
IP01435p

2

15

High-throughput

0.594

High

1174498

Q9W2P8
Homeobrain

2

20

High-throughput

0.594

High

1174499

Q9W3V7
Ataxin 1

2

17

High-throughput

0.594

High

662826

DISC
Protein disconnected

2

0

High-throughput

0.569

High

669593

OSKA
Maternal effect protein oskar

2

0

High-throughput

0.569

High

1174486

Q9VLF2
CCR4-NOT transcription complex subunit 9

2

0

High-throughput

0.569

High

1051899

KPEL
Serine/threonine-protein kinase pelle

1

0

Small-scale

0.549

High

458802

PER
Period circadian protein

2

17

Small-scale

0.545

High

1172217

TRH
Protein trachealess

2

11

Small-scale

0.545

High

1174475

Q8INY5
RE08003p1

2

1

High-throughput

0.544

High

195764

COS
Kinesin-like protein costa

1

6

High-throughput

0.541

High

594689

GROU
Protein groucho

1

20

High-throughput

0.541

High

652994

BAGP
Homeobox protein bagpipe

1

20

High-throughput

0.541

High

1172554

STAT
Signal transducer and transcription activator

1

3

High-throughput

0.541

High

1174488

Q9VMS5
Bub1 kinase, isoform A

1

14

High-throughput

0.508

High

60901

A2RVG7
Homeobox protein unc-4

1

20

High-throughput

0.494

High

1052699

Q058W3
IP14616p

1

20

High-throughput

0.494

High

1174474

Q8IMS8
FI20028p1

1

17

High-throughput

0.494

High

725856

PDM2A
POU domain protein 2, isoform A

1

20

High-throughput

0.492

High

120207

M9PCS1
Uncharacterized protein, isoform E

1

20

High-throughput

0.481

High

1174471

Q7KUL4
Intermediate neuroblasts defective

1

20

Small-scale

0.481

High

1174481

Q9VBQ1
LD31631p

1

17

High-throughput

0.481

High

451764

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

1

5

Small-scale

0.479

High

838591

TTKA
Protein tramtrack, alpha isoform

1

20

Small-scale

0.479

High

195207

RL39
Large ribosomal subunit protein eL39

1

4

High-throughput

0.464

High

1174484

Q9VJQ0
Uncharacterized protein, isoform B

1

1

High-throughput

0.464

High

1174468

Q6IL70
HDC10207

1

20

Small-scale

0.457

High

92303

D3DMM4
MIP15217p

1

1

High-throughput

0.451

High

99394

F3YDN7
IP15980p

1

1

High-throughput

0.451

High

1174473

Q8I942
IP11514p

1

1

High-throughput

0.451

High

1174500

Q9W481
LD15807p

1

1

High-throughput

0.451

High

117977

M9MRQ3
Uncharacterized protein

1

1

High-throughput

0.439

High

118124

M9MSK1
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

1174476

Q8IRR4
GM27849p

1

1

High-throughput

0.439

High

1174482

Q9VGE9
GH11519p

1

1

High-throughput

0.439

High

1174489

Q9VR90
Syntaxin 16

1

6

High-throughput

0.439

High

1174501

X2JEH3
Uncharacterized protein, isoform E

1

1

High-throughput

0.439

High

1174478

Q9GU66
Syntaxin

1

6

High-throughput

0.417

High

68545

A8JNG7
Uncharacterized protein

2

0

High-throughput

0.310

High

458843

SRYA
Serendipity locus protein alpha

2

0

High-throughput

0.310

High

1174491

Q9VTA8
RE35371p

2

0

High-throughput

0.310

High

1174493

Q9VVT4
IP10578p

2

0

High-throughput

0.310

High

1174495

Q9VZ18
GH14622p

2

0

High-throughput

0.310

High

1174496

Q9W0B3
Vacuolar protein sorting-associated protein VTA1 homolog

2

0

High-throughput

0.310

High

1174497

Q9W1B2
MICOS complex subunit MIC10

2

0

High-throughput

0.310

High

234835

O46070
EG:25E8.4 protein

1

0

High-throughput

0.265

Low

550551

MT2
Metallothionein-2

1

0

High-throughput

0.265

Low

1174472

Q86BM8
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.265

Low

1174487

Q9VME1
FI01864p

1

0

High-throughput

0.265

Low

1174492

Q9VTC7
Cuticular protein 67Fa2

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025