HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 12506011, 9632795, 9891995, 9658397, 23612964, 11606067, 24728074, 8596638, 9804835, 10978177, 16638574
Identification Methods affinity chromatography technology, pull down, two hybrid, far western blotting, coimmunoprecipitation, fluorescence polarization spectroscopy
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005911 - cell-cell junction
GO:0008286 - insulin receptor signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 724
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024