HitPredict

Interactor 1: EPOP (A6NHQ4)
Elongin BC and Polycomb repressive complex 2-associated protein (Proline-rich protein 28)
Gene: EPOP

Interactor 2: PHF1 (O43189)
PHD finger protein 1 (Protein PHF1) (hPHF1) (Polycomb-like protein 1) (hPCl1)
Gene: PHF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27705803, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0035098 - ESC/E(Z) complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 379 Hs			1 567
+	Hs
		65635 EPOP_HUMAN (1-379): 2.48e-45: 161: 100.00		PHF19_HUMAN (30-563): 0: 662: 39.09
+	Hs
		65643 EPOP_HUMAN (1-379): 2.48e-45: 161: 100.00		MTF2_HUMAN (27-564): 0: 643: 41.14
+	Mm
		1036634 EPOP_MOUSE (1-378): 1.88e-35: 135: 69.31		MTF2_MOUSE (27-564): 0: 654: 41.49
+	Hs
		1169537 SKDA1_HUMAN (218-375): 1.36e-15: 80.6: 30.77		PHF19_HUMAN (30-563): 0: 662: 39.09
+	Hs
		1169540 SKDA1_HUMAN (218-375): 1.36e-15: 80.6: 30.77		MTF2_HUMAN (27-564): 0: 643: 41.14
+	Hs
		1213581 CHAP1_HUMAN (2-319): 8.19e-09: 59.4: 13.54		PHF19_HUMAN (30-563): 0: 662: 39.09
+	Mm
		1297308 KMT2C_MOUSE (3-365): 5.63e-21: 97.1: 15.27		ASH2L_MOUSE (121-484): 2.23e-65: 226: 15.57
+	Hs
		1338281 KMT2C_HUMAN (3-365): 1.17e-18: 90.2: 14.43		ASH2L_HUMAN (162-484): 9.16e-65: 224: 15.13
+	Hs
		1361927 TITIN_HUMAN (2-350): 9.87e-09: 59.5: 12.22		ASH2L_HUMAN (162-484): 9.16e-65: 224: 15.13