Protein: PHF19
PHD finger protein 19 (Polycomb-like protein 3) (hPCL3)

Gene: PHF19
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q5T6S3

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

210294

PHF1
PHD finger protein 1

2

10

High-throughput

0.789

High

1155450

EZH2
Histone-lysine N-methyltransferase EZH2

11

20

Small-scale

0.758

High

1213564

PHF19
PHD finger protein 19

2

10

Small-scale

0.754

High

285328

EED
Polycomb protein EED

9

13

Small-scale

0.752

High

1137340

SUZ12
Polycomb protein SUZ12

9

6

Small-scale

0.752

High

216454

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

8

High-throughput

0.740

High

1213589

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

4

High-throughput

0.740

High

1213573

EZH1
Histone-lysine N-methyltransferase EZH1

5

20

High-throughput

0.720

High

65635

EPOP
Elongin BC and Polycomb repressive complex 2-associated protein

3

9

High-throughput

0.667

High

1158871

RBBP7
Histone-binding protein RBBP7

3

14

Small-scale

0.667

High

998414

H31
Histone H3.1

1

9

Small-scale

0.666

High

1213581

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

2

6

High-throughput

0.628

High

1213574

JARD2
Protein Jumonji

1

9

High-throughput

0.618

High

1213601

MTF2
Metal-response element-binding transcription factor 2

1

10

High-throughput

0.618

High

1066341

RBBP4
Histone-binding protein RBBP4

2

14

Small-scale

0.611

High

1146699

PCBP1
Poly(rC)-binding protein 1

2

1

Small-scale

0.611

High

1213582

LCOR
Ligand-dependent corepressor

2

2

High-throughput

0.611

High

478689

HXB5
Homeobox protein Hox-B5

2

3

High-throughput

0.606

High

997775

CSK21
Casein kinase II subunit alpha

2

3

High-throughput

0.606

High

1213586

THAP7
THAP domain-containing protein 7

2

3

High-throughput

0.606

High

1213593

THAP1
THAP domain-containing protein 1

2

3

High-throughput

0.606

High

1213596

RCOR3
REST corepressor 3

2

9

High-throughput

0.606

High

1213598

ZRAN1
Ubiquitin thioesterase ZRANB1

2

3

High-throughput

0.606

High

770393

T2FA
General transcription factor IIF subunit 1

2

0

High-throughput

0.602

High

1120020

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

2

0

High-throughput

0.602

High

1213588

SENP3
Sentrin-specific protease 3

2

0

High-throughput

0.602

High

1213595

TEX10
Testis-expressed protein 10

2

0

High-throughput

0.602

High

250649

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

Small-scale

0.586

High

913948

RBM5
RNA-binding protein 5

1

0

High-throughput

0.586

High

336688

BAG4
BAG family molecular chaperone regulator 4

2

0

High-throughput

0.580

High

1213569

IN80E
INO80 complex subunit E

2

0

High-throughput

0.580

High

1213571

SNIP1
Smad nuclear-interacting protein 1

2

0

High-throughput

0.580

High

1213577

ZN837
Zinc finger protein 837

2

0

High-throughput

0.580

High

1213583

YTDC1
YTH domain-containing protein 1

2

0

High-throughput

0.580

High

1213587

TSYL2
Testis-specific Y-encoded-like protein 2

2

0

High-throughput

0.580

High

1200968

ACTBL
Beta-actin-like protein 2

2

6

High-throughput

0.574

High

1213579

PDLI5
PDZ and LIM domain protein 5

2

1

High-throughput

0.574

High

246657

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.573

High

1213600

FBW1A
F-box/WD repeat-containing protein 1A

1

7

Small-scale

0.561

High

882715

EFTU
Elongation factor Tu, mitochondrial

2

2

Small-scale

0.558

High

1213575

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

1

High-throughput

0.553

High

1213585

LZTS2
Leucine zipper putative tumor suppressor 2

2

2

High-throughput

0.553

High

1127699

HIC1
Hypermethylated in cancer 1 protein

1

2

Small-scale

0.552

High

610366

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.536

High

1213568

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

7

High-throughput

0.536

High

1031907

NC2B
Protein Dr1

1

4

High-throughput

0.515

High

862657

UTRN
Utrophin

1

0

High-throughput

0.513

High

1009797

IN35
Interferon-induced 35 kDa protein

1

0

High-throughput

0.513

High

1213584

TBA1C
Tubulin alpha-1C chain

1

0

High-throughput

0.513

High

408916

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.493

High

714883

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.493

High

1025115

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.493

High

1169537

SKDA1
SKI/DACH domain-containing protein 1

1

5

High-throughput

0.489

High

1213567

HOMEZ
Homeobox and leucine zipper protein Homez

1

5

High-throughput

0.481

High

254159

CTND1
Catenin delta-1

1

2

Small-scale

0.479

High

406268

MYCN
N-myc proto-oncogene protein

1

4

High-throughput

0.479

High

557341

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

High-throughput

0.479

High

623378

RO52
E3 ubiquitin-protein ligase TRIM21

1

2

Small-scale

0.479

High

764820

CTNB1
Catenin beta-1

1

3

Small-scale

0.479

High

1180141

QRIC1
Transcriptional regulator QRICH1

1

5

High-throughput

0.479

High

1213565

AEBP2
Zinc finger protein AEBP2

1

5

High-throughput

0.479

High

570449

GFAP
Glial fibrillary acidic protein

1

1

High-throughput

0.470

High

285951

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.458

High

374666

RASH
GTPase HRas

1

0

High-throughput

0.458

High

764363

CTNA1
Catenin alpha-1

1

0

Small-scale

0.458

High

958963

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

1125886

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

0

High-throughput

0.458

High

1213590

MOG1
Ran guanine nucleotide release factor

1

0

High-throughput

0.458

High

1150732

SF01
Splicing factor 1

1

1

High-throughput

0.457

High

993608

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.438

High

518607

RAP2A
Ras-related protein Rap-2a

1

1

High-throughput

0.437

High

937519

CADH4
Cadherin-4

1

1

Small-scale

0.437

High

1193519

TTC31
Tetratricopeptide repeat protein 31

1

1

High-throughput

0.407

High

1213570

GSTCD
Glutathione S-transferase C-terminal domain-containing protein

2

0

High-throughput

0.328

High

1213592

NRBP2
Nuclear receptor-binding protein 2

2

0

High-throughput

0.328

High

1213591

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1124972

RCN2
Reticulocalbin-2

1

0

High-throughput

0.279

Low

1213578

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.279

Low

47340

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

49164

POTB3
POTE ankyrin domain family member B3

1

0

High-throughput

0.268

Low

622180

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low

1213572

BRK1
Protein BRICK1

1

0

High-throughput

0.268

Low

1213597

ATX10
Ataxin-10

1

0

High-throughput

0.268

Low

298186

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.249

Low

321262

ERLN2
Erlin-2

1

0

Small-scale

0.249

Low

464452

TSP1
Thrombospondin-1

1

0

Small-scale

0.249

Low

552023

ADT1
ADP/ATP translocase 1

1

0

Small-scale

0.249

Low

1013786

RL24
Large ribosomal subunit protein eL24

1

0

Small-scale

0.249

Low

1213566

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

1

0

Small-scale

0.249

Low

1213576

AP2M1
AP-2 complex subunit mu

1

0

Small-scale

0.249

Low

1213580

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

Small-scale

0.249

Low

1213599

EPCR
Endothelial protein C receptor

1

0

High-throughput

0.249

Low

1213594

TM160
Transmembrane protein 160

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025