HitPredict

Interactor 1: GBRB3 (P28472)
Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) (GABAAR subunit beta-3)
Gene: GABRB3

Interactor 2: GBRB3 (P28472)
Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) (GABAAR subunit beta-3)
Gene: GABRB3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 16537435, 24909990
Identification Methods cross-linking study, x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0004890 - GABA-A receptor activity
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007214 - gamma-aminobutyric acid signaling pathway
GO:0022851 - GABA-gated chloride ion channel activity
and 15 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 473
Hs

1 473
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Last updated: 15 Jul 2024