HitPredict

Interactor 1: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Interactor 2: 4EBP1 (Q13541)
Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I)
Gene: EIF4EBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12665511
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 360 Hs			1 118
+	Mm
		926411 MK01_MOUSE (10-360): 4.96e-158: 449: 99.72		4EBP1_MOUSE (1-118): 3.24e-55: 169: 90.68
+	Rn
		600434 MK03_RAT (15-357): 1.97e-152: 435: 88.63		4EBP1_RAT (1-118): 1.29e-58: 178: 92.37
+	Mm
		926396 MK01_MOUSE (10-360): 4.96e-158: 449: 99.72		4EBP2_MOUSE (2-118): 2.86e-53: 164: 57.98
+	Hs
		1038213 MK14_HUMAN (18-356): 7.86e-112: 332: 48.97		4EBP1_HUMAN (1-118): 3.72e-61: 184: 100.00