HitPredict

Interactor 1: PTPRD (P23468)
Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)
Gene: PTPRD

Interactor 2: NEK2 (P51955)
Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)
Gene: NEK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	22305495
Identification Methods	pull down, protein array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~fn3, I-set~Pkinase
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1912 Hs			1 445
+	Hs
		658899 PTPRD_HUMAN (1-1912): 0: 1666: 100.00		MARK2_HUMAN (2-425): 5.51e-123: 377: 23.56
+	Hs
		658925 PTPRD_HUMAN (1-1912): 0: 1666: 100.00		NEK1_HUMAN (6-272): 1.5e-51: 189: 42.32
+	Hs
		658933 PTPRD_HUMAN (1-1912): 0: 1666: 100.00		NEK6_HUMAN (7-262): 2.57e-50: 174: 37.69
+	Hs
		614701 PTPRA_HUMAN (1176-1912): 0: 796: 42.05		MARK2_HUMAN (2-425): 5.51e-123: 377: 23.56