HitPredict

Interactor 1: PSA2 (P23639)
Proteasome subunit alpha type-2 (Macropain subunit Y7) (Multicatalytic endopeptidase complex subunit Y7) (Proteasome component Y7) (Proteinase YSCE subunit 7)
Gene: PRE8

Interactor 2: RPN10 (P38886)
26S proteasome regulatory subunit RPN10
Gene: RPN10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	11805826, 32868373, 16429126, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 250 Sc			1 268
+	Hs
		700592 PSA5_HUMAN (3-250): 4.69e-92: 272: 30.04		PSMD4_HUMAN (1-236): 5.49e-119: 347: 49.15
+	Hs
		681607 PSA4_HUMAN (1-247): 3.04e-91: 271: 34.40		PSMD4_HUMAN (1-236): 5.49e-119: 347: 49.15
+	Hs
		700661 PSA5_HUMAN (3-250): 4.69e-92: 272: 30.04		Q5VWC4_HUMAN (1-236): 7.78e-119: 346: 49.15
+	Hs
		681664 PSA4_HUMAN (1-247): 3.04e-91: 271: 34.40		Q5VWC4_HUMAN (1-236): 7.78e-119: 346: 49.15
+	Hs
		933598 PSA6_HUMAN (2-250): 2.62e-91: 270: 32.54		PSMD4_HUMAN (1-236): 5.49e-119: 347: 49.15
+	Hs
		954830 PSA6_HUMAN (2-250): 2.62e-91: 270: 32.54		Q5VWC4_HUMAN (1-236): 7.78e-119: 346: 49.15
+	Hs
		165299 PSA7_HUMAN (1-248): 5.95e-90: 267: 32.00		PSMD4_HUMAN (1-236): 5.49e-119: 347: 49.15
+	Hs
		681134 PSA2_HUMAN (1-250): 4.63e-90: 267: 56.97		PSMD4_HUMAN (1-236): 5.49e-119: 347: 49.15
+	Sc
		661406 PSA3_YEAST (4-214): 4.64e-42: 145: 37.09		RPN10_YEAST (1-268): 3.44e-114: 330: 100.00
+	Sp
		314157 PSA4_SCHPO (5-214): 2.09e-41: 144: 38.39		RPN10_SCHPO (1-261): 5.82e-112: 323: 45.59