Interactor 1: GRIA1 (P23818)
Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)
Gene: GRIA1

Interactor 2: NMDE3 (Q01098)
Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C)
Gene: Grin2c

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17018287
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd
Common GO terms GO:0005886 - plasma membrane
GO:0045211 - postsynaptic membrane
GO:0098839 - postsynaptic density membrane
GO:0098978 - glutamatergic synapse
GO:1904315 - transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
and 1 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 907
Mm

1 1239
+ Mm
+ Hs
+ Rn
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+ Hs
+ Mm
+ Mm
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+ Rn
+ Rn
+ Hs
+ Hs
+ Mm
+ Rn
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+ Hs
+ Mm

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Last updated: 11Aug2025