HitPredict

Interactor 1: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Interactor 2: H2B1L (Q99880)
Histone H2B type 1-L (Histone H2B.c) (H2B/c)
Gene: H2BC13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1970 Hs			1 126
+	Hs
		667325 RPB1_HUMAN (1-1611): 0: 1900: 100.00		H2B2E_HUMAN (1-126): 2.17e-54: 168: 97.62
+	Hs
		667394 RPB1_HUMAN (1-1611): 0: 1900: 100.00		H2B1H_HUMAN (1-126): 2.45e-54: 168: 97.62
+	Hs
		256775 RPB1_HUMAN (1-1611): 0: 1900: 100.00		H2B1K_HUMAN (1-126): 4.52e-54: 167: 97.62
+	Hs
		449680 RPB1_HUMAN (1-1611): 0: 1900: 100.00		H2B1J_HUMAN (1-126): 2.67e-54: 167: 96.83
+	Hs
		667255 RPB1_HUMAN (1-1611): 0: 1900: 100.00		H2B1C_HUMAN (1-126): 4.42e-54: 167: 98.41
+	Hs
		667239 RPB1_HUMAN (1-1611): 0: 1900: 100.00		H2B1D_HUMAN (1-126): 1.28e-53: 166: 97.62
+	Sc
		381339 RPB1_YEAST (11-1593): 0: 1604: 49.00		H2B2_YEAST (5-125): 1.24e-35: 120: 71.90
+	Sc
		381340 RPC1_YEAST (11-1471): 0: 1348: 32.98		H2B2_YEAST (5-125): 1.24e-35: 120: 71.90
+	Hs
		339947 RPA1_HUMAN (1000-1476): 1.86e-34: 147: 16.93		H2B1B_HUMAN (1-126): 6.01e-54: 166: 96.03