Interactor 1: IL12A (P29459)
Interleukin-12 subunit alpha (IL-12A) (Cytotoxic lymphocyte maturation factor 35 kDa subunit) (CLMF p35) (IL-12 subunit p35) (NK cell stimulatory factor chain 1) (NKSF1)
Gene: IL12A

Interactor 2: I12R1 (P42701)
Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212)
Gene: IL12RB1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 8943050, 7911493
Identification Methods cross-linking study, competition binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0032729 - positive regulation of type II interferon production
GO:0035722 - interleukin-12-mediated signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 219
Hs

1 662
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024