Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.935

The method score is based on:

Property Details
Experiments 22231403, 36508083, 17361108, 21319273, 23602568, 17353931
Identification Methods affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000287 - magnesium ion binding
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
and 52 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 298
Hs

1 298
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Service provided by Combinatics, Japan

Last updated: 11Aug2025