HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: KC1E (P49674)
Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)
Gene: CSNK1E

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	29045831, 17218255, 11425858
Identification Methods	affinity chromatography technology, protein kinase assay, anti tag coimmunoprecipitation
Interaction Type	physical association, phosphorylation reaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2843 Hs			1 416
+	Mm
		1297032 Q8BNP7_MOUSE (1-1058): 0: 1471: 95.09		KC1E_MOUSE (1-416): 6.59e-135: 394: 98.80
+	Hs
		668526 APC_HUMAN (1-2843): 0: 1286: 100.00		KC1D_HUMAN (1-406): 3.9e-124: 367: 82.02
+	Hs
		668525 APC_HUMAN (1-2843): 0: 1286: 100.00		KC1A_HUMAN (2-325): 6.81e-115: 341: 69.44
+	Hs
		274118 ANR17_HUMAN (1869-2843): 7.16e-68: 258: 14.65		KC1A_HUMAN (2-325): 6.81e-115: 341: 69.44
+	Hs
		1006957 SRRM2_HUMAN (710-2256): 1.43e-21: 105: 9.26		KC1G2_HUMAN (3-348): 1.44e-118: 353: 50.28
+	Hs
		877157 MICA3_HUMAN (2257-2836): 1.01e-09: 66.9: 17.77		KC1D_HUMAN (1-406): 3.9e-124: 367: 82.02
+	Hs
		1273874 MICA3_HUMAN (2257-2836): 1.01e-09: 66.9: 17.77		AKT3_HUMAN (2-354): 9.56e-119: 355: 19.28