HitPredict

Interactor 1: CLH (P29742)
Clathrin heavy chain
Gene: Chc

Interactor 2: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	15710747
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0031410 - cytoplasmic vesicle
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1678 Dm			1 192
+	Hs
		925199 CLH1_HUMAN (1-1660): 0: 2995: 80.17		RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67
+	Hs
		960973 CLH1_HUMAN (1-1660): 0: 2995: 80.17		RHOJ_HUMAN (2-190): 4.27e-80: 239: 60.32
+	Hs
		545326 CLH1_HUMAN (1-1660): 0: 2995: 80.17		RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06
+	Hs
		950928 CLH1_HUMAN (1-1660): 0: 2995: 80.17		RHOG_HUMAN (1-192): 2.98e-77: 230: 67.19
+	Hs
		892321 CLH1_HUMAN (1-1660): 0: 2995: 80.17		RAC3_HUMAN (1-191): 1.08e-76: 229: 89.53
+	Hs
		893908 CLH1_HUMAN (1-1660): 0: 2995: 80.17		CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27
+	Hs
		900383 CLH1_HUMAN (1-1660): 0: 2995: 80.17		RHOA_HUMAN (5-192): 1.44e-74: 224: 54.79
+	Hs
		564482 CLH1_HUMAN (1-1660): 0: 2995: 80.17		RHOQ_HUMAN (4-192): 9.76e-73: 220: 62.05
+	Hs
		436257 CLH1_HUMAN (1-1660): 0: 2995: 80.17		RHOC_HUMAN (5-192): 2.38e-72: 218: 54.26