Interactor 1: BIP (P29844)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein homolog) (GRP-78 homolog) (Binding-immunoglobulin protein homolog) (BiP) (Heat shock 70 kDa protein cognate 3) (Heat shock protein cognate 72)
Gene: Hsc70-3

Interactor 2: FICD (Q8SWV6)
Protein adenylyltransferase Fic (dFic) (EC 2.7.7.108) (De-AMPylase Fic) (EC 3.1.4.-)
Gene: Fic

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 25395623, 29089387
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Fic~HSP70
Common GO terms GO:0005524 - ATP binding
GO:0034976 - response to endoplasmic reticulum stress
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 656
Dm

1 492
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024